Product Details
- Product Name- N-Hydroxy Phthalimide
- Chemical Formula- C8H5NO3
- Molar mass- 163.13 g·mol−1
- CAS No- 524-38-9
Papchem International LLC offer high quality, free flowing, white crystalline powder in customized packaging delivered to customer across the globe.
Product Description
N-Hydroxy Phthalimide is an important molecule in organic synthesis and in oxidation chemistry, as well as related areas, for it can serve both as a radical initiator and as an oxidation catalyst with great potential in medicinal chemistry and polymer chemistry. NHPI is preferred in oxidation chemistry because of its stability and efficient generation of the radicals under very mild conditions with no requirements of strong oxidants or high temperatures. Continuous Research is going on to develop new methodologies and applications with NHPI derivatives, mainly in green chemistry fields working for reducing environmental issues connected with the low ecological impact of the chemical process. NHPI is widely used in fine chemicals, pharmaceuticals, and agrochemical synthesis. NHPI and its derivatives ability to initiate radical reactions and assist controlled oxidation processes, makes them important in organic synthesis.
Applications
- Organic Synthesis: NHPI acts as a radical initiator in a wide range of organic reactions, mainly oxidation reactions. Under very mild conditions, it generates carbon-centered radicals from alkyl groups with great efficacy.
- Oxidation Reactions: NHPI catalyses oxidation reactions through co-catalysis or mediator in the activation of molecular oxygen or peroxide species. This makes NHPI of great importance in the oxidation of alcohols into carbonyl compounds and many other such transformations.
- Medicinal Chemistry: NHPI derivatives are under investigation for their potential applications in pharmaceuticals as prodrugs or in drug delivery systems by the potential of performing controlled oxidation processes.
- Polymer Chemistry: NHPI derivatives are applied in polymer chemistry, in particular, in cases of polymer surface modification and property enhancement by controlled oxidation reactions.
- Metal-Catalyzed Reactions: NHPI can be used as a ligand for metal-catalyzed reactions, thus modulating the reactivity and selectivity for various transformations.
- Agrochemicals: NHPI used in the manufacturing of agrochemicals.
- Nutraceuticals: NHPI is used in synthesis of some nutraceuticals.
- Material Sciences: Besides its application in organic synthesis and catalysis, NHPI derivatives are well-known in Material Sciences for the modification of surfaces and improvement of polymer properties by controlled oxidation reactions.
Product Specifications
| Test | Specification |
|---|---|
| Appearance | Off-White Powder to creamy fluffy powder |
| Purity | NLT 99% |
| Melting Point | 231°C to 235°C |
| Moisture Content (by KF) | NMT 0.5% |
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